Research Reports for 2013-2014
Research Grants Awards 1987-2005

2005

  • Risk of Neural Tube Defects in Association with Elevated C-Reactive Protein – Dr. J. Ray
2004

  •  Maternal Diabetes Mellitus and the Risk of Neural Tube Defects;
  •  Maternal Ethnicity and the Risk of Neural Tube Defects

2002-2005

  • “Developmental Issues Related to Cerebrospinal Fluid Transport and the Importance of the Extracranial Lymphatic System” This award has been granted for 3 years. This award is offered in partnership with SBHAC based on a 1:1 funding ratio with the Canadian Institutes of Health Research (CIHR).

2001

  •  Eye Movement Abnormalities and Cerebellar Dysmorphology in Children with Spina Bifida and Hydrocephalus

2000

  •  A Mechanical Investigation into the causes of Spina Bifida
  •  The Effects of Physical Activity and Bisphosphonate Supplementation on the Prevention and Reduction of “Secondary” Handicaps in Children with Spina Bifida

1999

  •  Developmental changes in CSF clearance mechanisms; relevance to pediatric hydrocephalus.
  •  “Self-Esteem and Social Support: Strengthening the Social Relationships of Young People with Spina Bifida”

1998

  •  No grants awarded
1997

  •  Identification of the Primary Lesion of the Spina Bifida and attempt to induce axonal growth using Polymer Matrix.
  •  Neural Tube Defects and Homocysteine Metabolism.

1996

  •  Renal Risk Project.
  •  Mesenchymal-Epithelial Transformation in Secondary Neurulation.
  •  Surgical Correction of Congenital Kyphosis and the Effects of Cordotomy on Bowel and Bladder Function in Myelomingocele.
  •  Toward Improved Diagnosis of Visual Learning Problems in Children with Hydrocephalus.

1995

  •  Mesenchymal-Epithelial Transformation in Secondary Neurulation.
  •  Timing Functions of the Cerebellum: Their Role in Motor & Language Skills with Children with Hydrocephalus.
  •  The Ventriculoperitoneal Shunt Design Trial.
  •  Sleep Disordered Breathing in Children with Myelomeningocele.

1994

  •  Expression Analysis of Vertebrate E (spl) Gene Homologues.
  •  Neural Tube Defects in the B.C. Sikh Population.
  •  Sleep Disordered Breathing in Children with Myelomeningocele.
  •  Conversational Patterns in Children with Myelomeningocele & Hydrocephalus.
  •  Development of the Father-Infant Relationship with an Infant who has Spina Bifida.

1993

  •  Does Amniotic Fluid Damage the Fetal Spinal Cord?
  •  Molecular Genetic Basis for Spina Bifida.
  •  Measuring Functional Outcome of Spine Surgery in Children with Spina Bifida.

1992

  •  Morbidity and Mortality in Hydrocephalic Children Associated with Cerebrospinal Fluid Shunt Valves: Slit & Core or Ball & Spring.
  •  Differentiation Waves During Formation of the Nervous System.
  •  Assessment of Methods for Rapid Diagnosis of Urinary Tract Infections in Children with Meningomyelocele.
  •  Molecular Genetics Basis for Spina Bifida.
  •  Support and Burden of Mothers of Children with Spina Bifida.

1991

  •  Comparison of Normal and Abnormal Neural Tube Closure.
  •  Mechanical Properties of Developing Neural Plate.
  •  Glucose Utilization in Neonatal Hydrocephalus.
  •  The Use of Stomach in Creating a Urinary Sphincter.

1990

  •  Mineral Analysis of Anencephalic Tissue and Control Tissue.
  •  The Effects of: (i) Experimentally Induced Hydrocephalus on the Cerebral Cortex and (ii) Vasopressin on Brain Water Content and Intracranial Pressure.
  •  Rotating Microscope for Observing Neurulation.
  •  Comparison of Bacterieurea in Subjects using Intermittent Catheterization: Sterile Catheters Versus Clean Reused Catheters.
  •  Gastric Muscularis as Physiological Urinary Sphincter.

1989

  •  The Effects of: (I) Experimentally induced Hydrocephalus on the Cerebral Cortex and (ii) Vasopressin on Brain Water Content and Intracranial Pressure. (2nd year of 3 year project)
  •  Early Brain Development. (3rd year)
  •  Chronic in vivo Evaluation of CSF Shunt Function in a Hydrophalic Model.
  •  Investigation of the Symplahtetic Nervous System in Myelodysplasia and its Relation to Vesico-Urethral Dysfunction.
  •  Identification of Genes Selectively Expressed in the Neuroectoderm of Amphibians During Neurulation.

1988

  •  The Effects of: (I) Experimentally induced Hydrocephalus on the Cerebral Cortex and (ii) Vasopressin on Brain Water Content and Intracranial Pressure. (1st year of 3 year project)
  •  Development of the Neural Tube. (2nd year)
  •  Study of the Surgical Release of Tethered Cords.
  •  Myelomeningocele Clinic Data Collection.

1987

  •  Mechanics of Early Neurulation. (1st year)
  •  To Assess the Long Term Neurological, Orthopaedic and Urological Consequences of the Surgical Release of Tethered Cords in Myelomeningocele Children.